GHK-Cu dosage reference: typical range 0.5 – 3 mg, Daily or split doses, cycle 8 weeks on, 4 weeks off (injectable). Titration chart, reconstitution math…
Naturally occurring tripeptide with copper binding. Multi-functional for wound healing, collagen synthesis, and anti-aging. Available injectable, topical, and in skincare.
Published protocol literature for GHK-Cu describes a typical range of 0.5 – 3 mg, dosed daily or split doses, over a cycle of 8 weeks on, 4 weeks off (injectable).
| Parameter | Reported value |
|---|---|
| Typical dose range | 0.5 – 3 mg |
| Frequency | Daily or split doses |
| Cycle length | 8 weeks on, 4 weeks off (injectable) |
| Route | Subcutaneous injection (most published protocols) |
| Diluent | Bacteriostatic water |
| Commonly stacked with | BPC-157, Epitalon (DNA repair), Thymosin Alpha-1 |
Protocols are usually titrated rather than started at the top of the range. The tiers below reflect how GHK-Cu dosing is commonly stepped in the published protocol literature.
| Tier | Dose | Frequency | Notes |
|---|---|---|---|
| Beginner | 0.5–1 mg | Daily (topical or SubQ) | Skin improvement, general healing |
| Intermediate | 1–2 mg | Daily | Joint and tissue benefits |
| Advanced | 2–3 mg | Daily or split doses | Maximum systemic anti-aging |
Concentration in mcg/mL equals vial milligrams multiplied by 1000, divided by the millilitres of bacteriostatic water added. Volume per dose in mL equals the target dose in mcg divided by that concentration. On a U-100 insulin syringe, multiply the volume in mL by 100 to read the units.
| Vial | Bacteriostatic water | Resulting concentration |
|---|---|---|
| 2 mg vial | 1 mL bacteriostatic water | 2,000 mcg/mL |
| 5 mg vial | 2 mL bacteriostatic water | 2,500 mcg/mL |
| 10 mg vial | 2 mL bacteriostatic water | 5,000 mcg/mL |
| State | Conditions | Shelf life |
|---|---|---|
| Lyophilized (Powder) | Refrigerate 2–8°C (36–46°F) or freeze | 12–24 months refrigerated; longer frozen |
| Reconstituted | Refrigerate 2–8°C only; no freezing | 21–30 days typically |
| In Transit | Insulated packaging; ice packs | Minimize time; avoid heat exposure |
| MK-677 (Oral) | Room temp okay; cool/dry preferred | Per manufacturer; typically 12+ months |
Dose ranges on this page summarise published research and practitioner protocol literature for GHK-Cu. They are a reference, not medical direction. All peptide products referenced are intended solely for research, investigational, or licensed professional use. They are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed medical practitioner before any personal or clinical use.
Published protocol literature for GHK-Cu generally describes 0.5 – 3 mg, administered daily or split doses. Individual protocols vary and should be set by a licensed practitioner.
Daily or split doses. Frequency is driven by half-life, so shorter-acting compounds are dosed more often.
Typical cycle length reported is 8 weeks on, 4 weeks off (injectable). Cycling exists to limit receptor desensitisation and to create assessment windows, not as a fixed rule.
2mg → 1ml bacteriostatic water; 5mg → 2ml bacteriostatic water; 10mg → 2ml bacteriostatic water. Concentration in mcg/mL equals vial milligrams times 1000 divided by millilitres of bacteriostatic water.
Both routes appear in the literature — topical formulations for skin/hair studies and injectable for systemic research models.