Epitalon dosage guide

Epitalon dosage reference: typical range 5 – 20 mg, Daily (PM), cycle 10–20 days on, 4–6 months off (unique cycling pattern). Titration chart…

Synthetic tetrapeptide that activates telomerase to maintain telomere length. Developed by Russian scientist Vladimir Khavinson; one of the most researched longevity peptides.

Published protocol literature for Epitalon describes a typical range of 5 – 20 mg, dosed daily (pm), over a cycle of 10–20 days on, 4–6 months off (unique cycling pattern).

Epitalon dosage at a glance

ParameterReported value
Typical dose range5 – 20 mg
FrequencyDaily (PM)
Cycle length10–20 days on, 4–6 months off (unique cycling pattern)
RouteSubcutaneous injection (most published protocols)
DiluentBacteriostatic water
Commonly stacked withThymosin Alpha-1 (immune/telomere), GHK-Cu (DNA repair), NAD+ precursors

Epitalon titration chart

Protocols are usually titrated rather than started at the top of the range. The tiers below reflect how Epitalon dosing is commonly stepped in the published protocol literature.

TierDoseFrequencyNotes
Beginner5 mgDaily (PM)Improved sleep, subtle energy
Intermediate10 mgDailyNoticeable vitality improvements
Advanced10–20 mgDailyFull anti-aging protocol

Reconstitution and concentration

Concentration in mcg/mL equals vial milligrams multiplied by 1000, divided by the millilitres of bacteriostatic water added. Volume per dose in mL equals the target dose in mcg divided by that concentration. On a U-100 insulin syringe, multiply the volume in mL by 100 to read the units.

VialBacteriostatic waterResulting concentration
2 mg vial1 mL bacteriostatic water2,000 mcg/mL
5 mg vial2 mL bacteriostatic water2,500 mcg/mL
10 mg vial2 mL bacteriostatic water5,000 mcg/mL

Protocol notes

What Epitalon is studied for

Storage after reconstitution

StateConditionsShelf life
Lyophilized (Powder)Refrigerate 2–8°C (36–46°F) or freeze12–24 months refrigerated; longer frozen
ReconstitutedRefrigerate 2–8°C only; no freezing21–30 days typically
In TransitInsulated packaging; ice packsMinimize time; avoid heat exposure
MK-677 (Oral)Room temp okay; cool/dry preferredPer manufacturer; typically 12+ months

Sources

Important

Dose ranges on this page summarise published research and practitioner protocol literature for Epitalon. They are a reference, not medical direction. All peptide products referenced are intended solely for research, investigational, or licensed professional use. They are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed medical practitioner before any personal or clinical use.

Frequently asked questions

What is a typical Epitalon dosage?

Published protocol literature for Epitalon generally describes 5 – 20 mg, administered daily (pm). Individual protocols vary and should be set by a licensed practitioner.

How often is Epitalon dosed?

Daily (PM). Frequency is driven by half-life, so shorter-acting compounds are dosed more often.

How long is a Epitalon cycle?

Typical cycle length reported is 10–20 days on, 4–6 months off (unique cycling pattern). Cycling exists to limit receptor desensitisation and to create assessment windows, not as a fixed rule.

How do you reconstitute Epitalon?

2mg → 1ml bacteriostatic water; 5mg → 2ml bacteriostatic water; 10mg → 2ml bacteriostatic water. Concentration in mcg/mL equals vial milligrams times 1000 divided by millilitres of bacteriostatic water.

Where does most Epitalon research come from?

The majority of published work originates from the St. Petersburg Institute of Bioregulation and Gerontology in Russia, with decades of accumulated data.