Epitalon

Epitalon is a synthetic 4-amino-acid peptide based on the pineal-gland peptide epithalamin. Research from the St. Petersburg Institute of Bioregulation…

Tetrapeptide studied for telomerase activity and circadian/pineal research.

Epitalon is a synthetic 4-amino-acid peptide based on the pineal-gland peptide epithalamin. Research from the St. Petersburg Institute of Bioregulation explores its effects on telomerase, melatonin rhythms, and aging biomarkers.

Overview

Epitalon is a short synthetic peptide derived from epithalamin, originally isolated from the pineal gland. The bulk of published research comes from long-running Russian gerontology programs.

Mechanism of action

Reported to upregulate telomerase activity and influence pineal-axis signaling in animal models.

Researched applications

Quick facts

PropertyDetail
ClassSynthetic tetrapeptide
SequenceAla-Glu-Asp-Gly
Half-lifeShort (minutes, plasma)

Other longevity & cellular peptides

Epitalon sits in our longevity & cellular category. These are the other compounds in the same category, useful when you are deciding which reference page to read next.

Storage and shelf life

StateConditionsShelf life
Lyophilized (Powder)Refrigerate 2–8°C (36–46°F) or freeze12–24 months refrigerated; longer frozen
ReconstitutedRefrigerate 2–8°C only; no freezing21–30 days typically
In TransitInsulated packaging; ice packsMinimize time; avoid heat exposure
MK-677 (Oral)Room temp okay; cool/dry preferredPer manufacturer; typically 12+ months

Sources

Review status

This reference page was last reviewed on 2026-06-13 by the Clarity Wellness editorial team.

Important

All peptide products referenced are intended solely for research, investigational, or licensed professional use. They are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed medical practitioner before any personal or clinical use.

Frequently asked questions

Where does most Epitalon research come from?

The majority of published work originates from the St. Petersburg Institute of Bioregulation and Gerontology in Russia, with decades of accumulated data.