Ipamorelin dosage reference: typical range 100–500 mcg, Daily at bedtime to 2–3× daily, cycle 12 weeks on, 4–6 weeks off; 5-on/2-off for longevity…
Highly selective growth hormone releasing peptide that doesn't significantly increase cortisol, prolactin, or ghrelin. The cleanest GHRP available; excellent for those sensitive to side effects.
Published protocol literature for Ipamorelin describes a typical range of 100–500 mcg, dosed daily at bedtime to 2–3× daily, over a cycle of 12 weeks on, 4–6 weeks off; 5-on/2-off for longevity. Reported half-life: about 2 hours.
| Parameter | Reported value |
|---|---|
| Typical dose range | 100–500 mcg |
| Frequency | Daily at bedtime to 2–3× daily |
| Cycle length | 12 weeks on, 4–6 weeks off; 5-on/2-off for longevity |
| Half-life | About 2 hours |
| Route | Subcutaneous injection (most published protocols) |
| Diluent | Bacteriostatic water |
| Commonly stacked with | CJC-1295 (the "gold standard" stack), BPC-157 (recovery), Tesamorelin (metabolic) |
Protocols are usually titrated rather than started at the top of the range. The tiers below reflect how Ipamorelin dosing is commonly stepped in the published protocol literature.
| Tier | Dose | Frequency | Notes |
|---|---|---|---|
| Beginner | 100–200 mcg | Daily at bedtime | Gentle intro; better sleep, mild pumps |
| Intermediate | 200–300 mcg | 2× daily (AM/PM) | Noticeable mass; protein surplus recommended |
| Advanced | 300–500 mcg | 2–3× daily | Peak anabolism; monitor for water retention |
Concentration in mcg/mL equals vial milligrams multiplied by 1000, divided by the millilitres of bacteriostatic water added. Volume per dose in mL equals the target dose in mcg divided by that concentration. On a U-100 insulin syringe, multiply the volume in mL by 100 to read the units.
| Vial | Bacteriostatic water | Resulting concentration |
|---|---|---|
| 2 mg vial | 1 mL bacteriostatic water | 2,000 mcg/mL |
| 5 mg vial | 1 mL bacteriostatic water | 5,000 mcg/mL |
| 10 mg vial | 2 mL bacteriostatic water | 5,000 mcg/mL |
| State | Conditions | Shelf life |
|---|---|---|
| Lyophilized (Powder) | Refrigerate 2–8°C (36–46°F) or freeze | 12–24 months refrigerated; longer frozen |
| Reconstituted | Refrigerate 2–8°C only; no freezing | 21–30 days typically |
| In Transit | Insulated packaging; ice packs | Minimize time; avoid heat exposure |
| MK-677 (Oral) | Room temp okay; cool/dry preferred | Per manufacturer; typically 12+ months |
Dose ranges on this page summarise published research and practitioner protocol literature for Ipamorelin. They are a reference, not medical direction. All peptide products referenced are intended solely for research, investigational, or licensed professional use. They are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed medical practitioner before any personal or clinical use.
Published protocol literature for Ipamorelin generally describes 100–500 mcg, administered daily at bedtime to 2–3× daily. Individual protocols vary and should be set by a licensed practitioner.
Daily at bedtime to 2–3× daily. Frequency is driven by half-life — Ipamorelin has a reported half-life of about 2 hours, so shorter-acting compounds are dosed more often.
Typical cycle length reported is 12 weeks on, 4–6 weeks off; 5-on/2-off for longevity. Cycling exists to limit receptor desensitisation and to create assessment windows, not as a fixed rule.
2mg → 1ml bacteriostatic water; 5mg → 1ml bacteriostatic water; 10mg → 2ml bacteriostatic water. Concentration in mcg/mL equals vial milligrams times 1000 divided by millilitres of bacteriostatic water.
No. Ipamorelin is a peptide secretagogue that supports endogenous GH release; it is not an anabolic steroid.
Published research shows Ipamorelin is unusually clean on cortisol and prolactin compared to older GHRPs — a major reason it's preferred in modern protocols.