GHK-Cu

GHK-Cu is a naturally occurring copper-binding tripeptide with decades of dermatological literature. Research focuses on collagen synthesis, wound healing…

Copper-binding tripeptide widely studied in skin and hair research.

GHK-Cu is a naturally occurring copper-binding tripeptide with decades of dermatological literature. Research focuses on collagen synthesis, wound healing, and hair-follicle biology.

Overview

GHK-Cu is a naturally occurring tripeptide that binds copper. It has decades of dermatological and regenerative-research literature focused on collagen, wound repair, and follicle biology.

Mechanism of action

Modulates copper transport and influences gene expression linked to collagen synthesis, antioxidant defense, and tissue remodeling.

Researched applications

Quick facts

PropertyDetail
ClassCopper-binding tripeptide
Sequence length3 amino acids
Molecular weight~340 Da (peptide) + Cu
RoutesTopical (cosmetic research) and injectable (systemic research)
StorageLyophilized: freezer. Reconstituted: 2–8 °C

GHK-Cu head-to-head

Storage and shelf life

StateConditionsShelf life
Lyophilized (Powder)Refrigerate 2–8°C (36–46°F) or freeze12–24 months refrigerated; longer frozen
ReconstitutedRefrigerate 2–8°C only; no freezing21–30 days typically
In TransitInsulated packaging; ice packsMinimize time; avoid heat exposure
MK-677 (Oral)Room temp okay; cool/dry preferredPer manufacturer; typically 12+ months

Sources

Review status

This reference page was last reviewed on 2026-06-13 by the Clarity Wellness editorial team.

Important

All peptide products referenced are intended solely for research, investigational, or licensed professional use. They are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed medical practitioner before any personal or clinical use.

Frequently asked questions

Is GHK-Cu used topically or by injection in research?

Both routes appear in the literature — topical formulations for skin/hair studies and injectable for systemic research models.