Cognitive peptide protocols — semax, selank, cerebrolysin, dihexa. Dose ranges, delivery routes, cycle length, and the neurotrophic research behind each.
Nootropic peptides are studied for neurotrophic and neuroprotective effects rather than acute stimulation. Semax and selank are the most referenced and are commonly delivered intranasally, while dihexa and cerebrolysin appear in the literature around BDNF signalling and neural repair. Cycles are typically short.
Protocols covered: MOTS-c, Semax, Selank, Dihexa, NA-Selank / NA-Semax Amidate, P21.
MOTS-c: 5 – 15 mg, 2–3×/week. Cycle: 4–8 weeks on, 2–4 weeks off. Semax: 200 – 900 mcg, Daily to 2× daily intranasal. Cycle: 10–14 days on, 7–10 days off. Selank: 200 – 1200 mcg, Daily to 2× daily intranasal. Cycle: Continuous low-dose acceptable; 4 weeks high-dose then 2 weeks off. Dihexa: 5 – 30 mg, Daily oral (morning). Cycle: 8–12 weeks on, 4 weeks off. NA-Selank / NA-Semax Amidate: 150 – 600 mcg, Daily to 2× daily intranasal. Cycle: 10–14 days on, 7–10 days off. P21: 500 mcg – 2 mg, Daily SubQ. Cycle: 4–8 weeks on, 2–4 weeks off.