BPC-157

BPC-157 is a synthetic 15-amino-acid peptide derived from a protein in human gastric juice. It is among the most-studied research peptides for soft-tissue…

A 15-amino-acid peptide widely studied for tissue repair and gut integrity.

BPC-157 is a synthetic 15-amino-acid peptide derived from a protein in human gastric juice. It is among the most-studied research peptides for soft-tissue repair, tendon healing, and gastrointestinal protection — almost entirely in animal models to date.

Overview

BPC-157 is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It is one of the most extensively studied research peptides in the recovery space, with a deep preclinical literature focused on tendon, ligament, muscle, and gastrointestinal tissue.

Mechanism of action

Research suggests BPC-157 upregulates growth factor receptors (VEGFR2, FAK-paxillin signaling) and modulates the nitric oxide system, supporting angiogenesis and tissue regeneration in animal models.

Researched applications

Quick facts

PropertyDetail
ClassPentadecapeptide
Sequence length15 amino acids
Molecular weight~1,419 Da
Half-life~4 hours (SC, rodent)
Typical research dose200–500 mcg/day (preclinical)
StorageLyophilized: freezer. Reconstituted: 2–8 °C, ≤28 days
DiluentBacteriostatic water

Reconstitution & handling

Typically reconstituted with bacteriostatic water; refrigerate after reconstitution.

Half-life

Reported half-life: Approximately 4 hours (subcutaneous, animal models).

Commonly researched alongside

Other healing & recovery peptides

BPC-157 sits in our healing & recovery category. These are the other compounds in the same category, useful when you are deciding which reference page to read next.

BPC-157 head-to-head

Storage and shelf life

StateConditionsShelf life
Lyophilized (Powder)Refrigerate 2–8°C (36–46°F) or freeze12–24 months refrigerated; longer frozen
ReconstitutedRefrigerate 2–8°C only; no freezing21–30 days typically
In TransitInsulated packaging; ice packsMinimize time; avoid heat exposure
MK-677 (Oral)Room temp okay; cool/dry preferredPer manufacturer; typically 12+ months

Sources

Review status

This reference page was last reviewed on 2026-06-13 by the Clarity Wellness editorial team.

Important

All peptide products referenced are intended solely for research, investigational, or licensed professional use. They are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Consult a licensed medical practitioner before any personal or clinical use.

Frequently asked questions

What is BPC-157 used for in research?

BPC-157 is studied primarily for soft-tissue healing, tendon and ligament repair, and gastrointestinal protection in animal models.

Is BPC-157 FDA-approved?

No. BPC-157 is not approved by the FDA for any human use and is sold for research, investigational, or licensed professional use only.

How is BPC-157 typically administered in studies?

Most published research uses subcutaneous or intraperitoneal injection. Always defer to a licensed practitioner for any clinical context.

What pairs well with BPC-157 in research?

TB-500 is the most commonly studied companion molecule — the two target complementary repair pathways.